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張明超照片
Ming-Chau Chang

Ph.D. Professor

Office: 榮總中正樓18樓 510室 分機 28757557#121

Lab:

mcchang@vghtpe.gov.tw

Research

The main research focus of this laboratory include:

  1. The relationship between Mitochondrial DNA mutations and Degenerative Joint Disease.
  2. Augmentation of screws with PMMA cement inpatients with severe osteoporosis spinal deformity.


Faculty Porfiles

張明超教授

Education

  • Bachelor of Medicine National Defense Medical Center Taipei, Taiwan,

Career and Experience

  • Current Positions:
    - Now, Chief, Division of Spine Surgery Orthopedics department, Taipei Veterans General Hospital,
    - Now, Professor, National Yang-Ming University,
    - Now, Director, Taiwan Orthopedic Association ,
  • Experiences:
    - President, Taiwan Society of Minimally Invasive Spine Surgery,
    - Supervisor, Taiwan Orthopedic Association,
    - Clinical fellow in Spine center Rush University Medical Center Chicago, U.S.A.,
    - Research fellow Micro vascular Research Lab, Mayo Clinic, U.S.A.,
    - Attending Surgeon Orthopedics department, Taipei Veterans General Hospital,

Medical Expertise

  • Minimally Invasive Spine Surgery combined with navigation system Spine Surgery on HIVD, Spondylosis, Spondylolisthesis,

License

  • Taiwan Orthopedic Association
  • Pacific and Asian Society of the Minimally Invasive Spine Surgery
  • Taiwan Society of Spine Surgery

PUBLICATIONS

  1. Chou PH, Ma HL, Wang ST, Liu CL, Chang MC, Yu WK. Fusion may not be a necessary procedure for surgically treated burst fractures of the thoracolumbar and lumbar spines: a follow-up of at least ten years. J Bone Joint Surg Am. 2014 Oct 15;96(20):1724-31
  2. Chang MC, Kao HC, Ying SH, Liu CL. Polymethylmethacrylate augmentation of cannulated pedicle screws for fixation in osteoporotic spines and comparison of its clinical results and biomechanical characteristics with the needle injection method. J Spinal Disord Tech. 2013 Aug;26(6):305-15
  3. Tsai CE, Lee FT, Chang MC, Yu WK, Wang ST, Liu CL. Primary cervical osteomyelitis J Chin Med Assoc. 2013 Nov;76(11):640-7 (corresponding author) (SCI)
  4. Hung-Kai Weng R, Chang MC, Feng SW, Wang ST, Liu CL, Chen TH. Progressive growth of arachnoid cysts with cauda equina syndrome after lumbar spine surgery. J Chin Med Assoc. 2013 Sep;76(9):527-31(corresponding author) (SCI)
  5. Yew TL, Chang MC, Hsu YT, He FY, Weng WH, Tsai CC, Chiu FY, Hung SC. Efficient expansion of mesenchymal stem cells from mouse bone marrow under hypoxic conditions. J Tissue Eng Regen Med. 2013 Dec;7(12):984-93. Epub 2012 May 24 (Co-first author) (SCI)
  6. Wang CS, Feng SW, Huang LJ, Yu JK, Chang MC, Wang ST, Liu CL. Atypical mycobacterial spondylitis as a challenging differential diagnosis to metastatic disease of the spine: a case report. Eur J Orthop Surg Traumatol. 2013 Nov;23 Suppl 2:135-9 (SCI)
  7. Lin CP, Ma HL, Wang ST, Liu CL, Yu WK, Chang MC. Surgical results of long posterior fixation with short fusion in the treatment of pyogenic spondylodiscitis of the thoracic and lumbar spine: a retrospective study. Spine (Phila Pa 1976). 2012 Dec 1;37(25):E1572-9. (SCI)
  8. Szu-Han Ying, Hung Chan Kao, Ming-Chau Chang, Wing-Kuang Yu, Shih-Tein Wang, Chien-Lin Liu. Fixation strength of PMMA-augmented pedicle screws after depth adjustment in a synthetic bone model of osteoporosis. Orthopedics. 2012 Oct;35(10):e1511-6. (corresponding author) (SCI)
  9. Yi-An Lee, Che-Li Lin, Ming-Chau Chang, Chien-Lin Liu,Tain-Hsiung Chen, Shih-Chang Lai. Subsequent vertebral fracture after vertebroplasty: Incidence and analysis of risk factors Spine 2012 Feb.1;37(3):179-83.. (corresponding author) (SCI)
  10. Chien-Shun Wang, His-Hsien Lin, Jung-Kuang Yu, Ming-Chau Chang,Shih-Tien Wang, Chien-Lin Liu. Comparison of the adjacent-level fracture rate between instrumented fusion plus vertebroplasty and vertebroplasty alone in osteoporotic spine. Formosan Journal of Musculoskeletal Disorders 2012 Feb:3(1): 9-13.
  11. Ming-Hsien Hu, Hung TaH.Wu, Ming-Chau Chang*, Wing-Kwang Yu, Shih-Tien Wang, Chien-Lin Liu. Polymethylmethacrylate Augmentation of the Pedicle Screw:The cement distribution in the vertebral body. European spine journal: 2011 Aug(20):1281-88. (corresponding author) (SCI)
  12. Sheng-Wen Feng, Ming-Chau Chang*, Hung-Ta Wu, Jung-Kuang Yu,Shih-Tien Wang, Chien-Lin Liu. Is vacumn ohenomenon a benign lesin? European spine journal: 2011 Aug (20):1341-48. (corresponding author) (SCI)
  13. Y.J.Wei K.S. Tsai, L.C.Lin, Y.T.Lee, C.W.Chi, M.C. Chang, T.H. Tsai, S.C. Hung. Catechin stimulates osteogenesis by enhancing PP2A activity in human mesenchymal stem cells. Osteoporosis Int. 2011May 22(5):1469-79 (SCI)
  14. Tu-Lai Yew, Fang-Yao Chiu, Chih-Chien Tsai, Hen Li Chen, Wei-Ping Lee, Yann-Jang Chen, Ming-Chau Chang, Shih-Chieh Hung. Knockdown of p21(Cip1/Waf1) enhances proliferation, the expression of stemness markers, and osteogenic potential in human mesenchymal stem cells. Aging Cell 2011 Apr 10(2):349-61 (SCI)
  15. Li CH, Chang MC, Liu CL, Chen TS.Li CH, Osteoporotic burst fracture with spinal canal compromise treated with percutaneous vertebroplasty. Clin Neurol Neurosurg. 2010 Oct;112(8):678-681. (corresponding author) (SCI)